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Eirik Østmo / Torger Grytå

VI seminar 2021 #5 – Designing deep learning studies in medical diagnostics and beyond

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Presenter: Andreas Kleppe, Institute for Cancer Genetics and Informatics, Oslo University Hospital, and Department of Informatics, University of Oslo

Andreas Kleppe

Abstract: Many deep learning studies are not designed to provide unbiased estimation of the system's performance in the intended application. Reports of overoptimistic estimates and opportunities may inflate the expectation of what is currently possible, misguide resource allocation, and hamper the progression of the field. In this talk, we will look into how the performance of a deep learning system in an intended application could be estimated more reliably than what is currently common practice, even if restricted to using retrospective data. To exemplify how some choices of the learning setup may influence the generalisability of the system, results will be presented from experiments where the goal is to predict whether a patient will eventually die from a cancer or survive following surgery. The presentation builds upon the publications:

The Lancet: Deep learning for prediction of colorectal cancer outcome: a discovery and validation study.

Nature: Designing deep learning studies in cancer diagnostics.

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